Chairs : Pedro MARQUES (PORTUGAL), Juan Manuel JIMÉNEZ VACAS (UNITED KINGDOM)

Molecular mechanisms of cavernous sinus invasion by pituitary adenomas: in vitro studies and in vivo investigations in a rat model of invasive pituitary tumorigenesis obtained by stereotactic pituitary GC cells injection

Circulating microRNAs as predictors for dopamine agonists in hyperprolactinemic patients with pituitary adenoma

Effect of a novel somatostatin receptor 5/3 agonist, HTL0030310, on human GH- and ACTH-secreting pituitary adenomas in vitro  

Xq26.3 duplications in X-linked acrogigantism (X-LAG) disrupt a topologically associating domain (TAD) and rewire GPR101-enhancer interactions

Morphological and molecular evidence of macroautophagy in pituitary tumors

New provocation test using MDMA (‘Ecstasy’) demonstrates Oxytocin deficiency in patients with central diabetes insipidus

Association between use of systemic and inhaled glucocorticoids and changes in brain volume and white matter microstructure: a cross-sectional UK Biobank study

CRN04894: an oral, nonpeptide ACTH (MC2) receptor antagonist decreaseds basal and stimulated cortisol secretion in healthy volunteers 

Chairs : Yona GREENMAN (ISRAEL), Anne BARLIER (FRANCE)

Transcriptomic Signature of Pituitary NeuroEndocrine Tumors (PitNETs) aggressiveness

Single nucleus multiomics identifies inter- and intra-donor heterogeneity in pituitary neuroendocrine tumors/pituitary adenomas

High-risk pituitary adenomas: lessons learned and summary on the eve of the new classification - a clinicopathologic case series from the referral pituitary center.

Neoadjuvant or Adjuvant treatment of mutant BRAF-V600E papillary Craniopharyngioma (Swecranio1-21)

Serum soluble alpha klotho in patients with growth hormone deficiency

Immunoglobulin G is an oxytocin-binding protein in plasma – role in oxytocin receptor activation and relevance to aggressive behavior  

Chairs : Atanaska ELENKOVA (BULGARIA)

Increased cancer risk in acromegaly patients – the never ending controversy

Real-time detection of acromegaly from facial images with artificial intelligence

The MPOWERED Phase 3 Trial : Oral Octreotide Outcomes based on IGF-I Response Criteria

Improvements in hypertension and diabetes mellitus with osilodrostat in Cushing’s disease patients: Exploratory analyses from the Phase III LINC 3 study

Molecular dissection of the GIP/GIPR axis in a stable cell model of GH-secreting pituitary adenomas

Implementation of functional imaging using 11C-methionine PET-CT co-registered with MRI for advanced surgical planning and decision making in prolactinoma surgery

Efficacy and predictive factors of response to immunotherapy in pituitary carcinomas and aggressive pituitary tumors: a French cohort study

High prevalence of genetic predisposition in young men and women with lactotrop macroadenomas

Prolactinomas: resistance assessment via metabolomic characteristics

Impact of the diagnostic delay of acromegaly on bone health: data from a real life and long term follow-up experience

Clinical and translational evidence of metformin and simvastatin additive antitumor effects in glioblastoma via senescence-state

Somatic hotspot variants rarely coexist with germline drivers of Cushing’s disease

Clinicopathological characteristics, clinical outcome, and prognostic factors for pituitary carcinomas: lessons from a systematic review of 207 cases

Dissecting the in vitro efficacy of octreotide and cabergoline in GH- and GH/PRL-secreting pituitary tumors

Somatostatin and ghrelin systems characterization and therapeutic potential in liver diseases

Neoadjuvant B-RAF and MEK inhibitor targeted therapy for Adult Papillary Craniopharyngiomas: A new treatment paradigm

Volumetric BMD and bone strength estimates on QCT-based finite element analysis are impaired in patients with Cushing’s syndrome in long-term remission

Prevalence of somatic SF3B1 mutations in lactotroph tumours

Lysine demethylase KDM1A and ectopic expression of GIP-receptor in somatotroph adenomas

Discrimination of pituitary neuroendocrine tumours by Raman spectroscopy

Central diabetes insipidus from a patients’ perspective: management, psychological co-morbidities and re-naming of the condition

Circulating miR-28-5p is a potential biomarker of sarcopenia in patients with Cushing’s syndrome in remission

The effect of glucose dynamics on plasma copeptin levels upon glucagon, arginine, and macimorelin stimulation in healthy adults

Resistance to cabergoline treatment in human primary non-functioning pituitary tumour cells

Cabergoline add-on therapy in patients with uncontrolled acromegaly under somatostatin analogues – a multicenter, retrospective, cohort study of non-irradiated patients applying current criteria for disease control  

Long-term treatment with oral paltusotine for acromegaly: Results from the ACROBAT Advance study 

Debio 4126, a new 3-month octreotide formulation, provides sustained release of octreotide, as well as enhanced bioavailability and similar suppression of insulin-like growth factor 1 (IGF-1), compared to monthly Sandostatin LAR in healthy volunteers - interim results

Genetic aspects of adrenal incidentalomas

Outcomes in patients receiving oral octreotide capsules related to time from last somatostatin receptor ligand injection: analysis from the MPOWERED Phase 3 study

Clinical-imagine asessment of agressive pituitary adenomas

Patterns of somatostatin receptor ligand dosage and titration in patients with acromegaly: a real-world evidence study

First-generation somatostatin receptor ligands in the treatment of acromegaly: real-world patient journey

Treatment of hypothalamic obesity with GLP-1 agonists and extreme diet in a patient with hypothalamic inflammatory infiltration

Clinical case of syndrome of inappropriate secretion of antidiuretic hormone (SIADH) with uncertain localization

Vanishing pituitary lesion with intermittent central adrenal insufficiency

ACROMEGALY DUE TO  A GH-SECRETING PITUITARY ADENOMA IN THE SPHENOID SINUS

Morning and evening concentrations of salivary aldosterone and cortisol throughout the menstrual cycle in healthy women

Observation of bone mineral density in Cushing syndrome

The various clinical outcomes of giant prolactinomas in men

The endoscopic endonasal resection of giant pituitary neuroendocrine tumors - case series from the referral pituitary center.

Results of surgical treatment of the Rathke cleft cysts with endoscopic endonasal cyts evacualtion – clinical series from pituitary referral center.

Impact of the micro nutriments’ deficit on the functional disorders for diabetic menopause women.

Health-Related Quality of Life Burden in Endogenous Cushing’s Syndrome: A Retrospective Medical Chart Audit Study

Gonadotroph Adenomas. A Single-Center Study of 112 cases.

Hypothalamic neuropeptides as biomarkers of diabetes insipidus.

A rare case of dermoid cyst as a cause of short stature, precocious puberty, optic nerve hypoplasia, and hypopituitarism

Cardio-metabolic risk in acromegaly patients: a study of cardiac magnetic resonance imaging

Age-dependent differences in acromegaly at diagnosis

Impaired insulin secretion without changes in insulin sensitivity explains hyperglycemia in patients with acromegaly treated by pasireotide LAR

Pituitary dysfunction in histiocytosis at diagnosis and follow-up: a single tertiary center experience

Cardio-metabolic risk in Cushing’s syndrome patients: a study of cardiac magnetic resonance imaging

Resistant and aggressive prolactinoma treated with temozolomide

First line treatment with 177Lu-Dotatate in a patient with miliary liver metastases and carcinoid syndrome from a midgut neuroendocrine tumor

Hpa axis disregulation due to impaired glucocorticoid negative feedback in patients with chronic kidney disease

A novel flow cytometry-based method to study lymphocytes present in low cell numbers infiltrating non-functional and growth-hormone secreting pituitary adenomas

Dilated cardiomyopathy, a rare and reversible manifestation of the glucagonoma syndrome

Thyrotropin-secreting pituitary adenoma: a case in which postoperative surveillance made a difference

Cyclin-dependent kinase 4 (cdk4) regulates the myelin sheath of hypothalamic neurons

RELATIONSHEEP BETWEEN COVID-19 AND VITAMIN D.

Late-night salivary cortisol versus urinary free cortisol in the monitorization of cushing's syndrome patients treated with steroidogenesis inhibitors

Forty-two patients with thyrotropin-secreting pituitary adenomas: clinical characteristics and therapeutic outcomes

metabolically healthy obesity: and if the key was the quality of sleep?

Impact of preanalytical conditions and biological variables on urinary concentrations of soluble alpha klotho, a novel biomarker of growth hormone activity

“Complexity of Carney complex”: a case series form a single expert center for rare endocrine diseases

Assessing the immune gene and cellular networks within human non-functioning and growth-hormone secreting pituitary adenomas via transcriptomic and pathway analysis

The partial response to first generation somatostatin analogues guides the choice and may predict the outcome of second line therapies with pasireotide lar: data from a real life experience

Prospective assessment of 11C-Methionine PET-MRI performance to localize corticotroph pituitary microadenomas

Features of carbohydrate disorders in Cushing Syndrome 

Declining hemoglobin levels may serve as a marker for disease duration in male macroprolactinoma: a proof-of-concept retrospective study

A pituitary macroadenoma revealed by an ischemic stroke: a case report

Pituitary adenoma consistency affects postoperative hormone function: a retrospective study

Comparative transcriptomics of functional vs non-functional pituitary neuroendocrine tumors

Incidental Discovery of Pituitary Insufficiency after Non-pituitary Surgery

Cushing syndrome in older women: age-related differences in disease origin and clinical manifestations

The immune cell profiling in acromegalic patients. Preliminary results from a case-control study

macroprolactinoma in a postmenopausal woman: a case report

Predictors of response to steroid therapy in primary anterior or pan-hypophysitis

Potential benefits of sleep medicine in acromegalics: preliminary results from a case-control study

Tumor volume assessment in consecutive newly-diagnosed patients with acromegaly- evaluation of two methods

MALFD prevalence in a cohort of patients with Cushing´s Disease

A rare aggressive tumor of the sellar region: atypical teratoid/rhabdoid tumor

Thyrotrophynoma induced hyperthyroidism: what is the best management?

Pituitary macroadenoma and pregnancy: a case report

Gender Differences in Pituitary Somatotropinomas Size After Radiation Therapy

ACTH-dependent severe hypercortisolaemia treated with osilodrostat and etomidate combination therapy - a case report. 

MEN-1 phenotype or a series of unfortunate events?

The challenging  management of aggressive, giant silent corticotroph PiTNET in a young male patient

Hyperprolactinemia is common in geriatric patients: A descriptive study

Increased innervation of the hypothalamic paraventricular nucleus by the AgRP and α-MSH axonal projections in germ-free mice

Salivary cortisol concentrations in children suffering from depression treated with omega-3 fatty acids

Adult Langerhans’ cell histiocytosis as polidipsic - poliuric syndrome in Covid Times

 Telemedicine as a good tool for monitoring Acromegalic outpatients during COVID-19 pandemic

Osilodrostat in patients with persistent or recurrent Cushing's Disease: a real-life single center experience  

Obesity and reproductive disorders in women.

Clinical features of non-functioning sellar and parasellar lesions in the transition age: a retrospective Italian multi-centre study

Cardiac morphology and function in adult patients with growth hormone deficiency – a cross-sectional case-control study

Optimization of medical therapy in patients with acromegaly

TGFBR3L in Non-Functioning Pituitary Neuroendocrine Tumours

Overnight dexamethasone suppression test: a valuable measure of medical treatment efficacy in ACTH-dependent Cushing’s Syndrome  

Ectopic ACTH syndrome in lung carcinoids – a case series

MEDICAL TREATMENT IN CUSHING'S DISEASE - EXPERIENCE OF A TERTIARY CARE CENTRE

Immunohistochemichal expression of ephrin receptor (EPH)-A4, -A5, -B2, -B5 and SSTR2a and -5  in pituitary lesions

Cushing syndrome and pregnancy: a single tertiary center experience

Baseline clinical and treatment characteristics in a Dutch national cohort of patients with prolactinoma

Stem cell markers are associated with the regulators of the gonadotroph axis in gonadotroph NF-PitNETs

Predictive Factors for Acromegaly Remission after Transsphenoidal Surgery in a Portuguese tertiary care center

Ectopic production of ACTH in the adrenal medulla (clinical case)

  " Characteristics of the clinical picture of Type III Polyglandular Autoimmune Syndrome ” 

The relatives’ quality of life and perception of the disease differ between Acromegaly and Cushing’s syndrome in remission

Craniopharyngiomas in Adults : a cohort study of 151 patients

Contribution of functional imaging in the follow-up of a patient with pituitary macroadenoma, paraganglioma, renal tumor, and SDHC gene variant.  

Case report: Safety and usefulnes of Metyrapone for the control of hypercortisolism in a complex patient with Cushing´s disease

Cushing’s syndrome in the elderly: data from ercusyn  

 Characteristics of disorders of reproductive function in women of fertile age with  Cushing syndrome in the Republic of Uzbekistan

Pituitary apoplexy and COVID-19 infection/vaccination

CLINICAL FEATURES OF ACROMEGALY IN THE KHOREZM REGION

Somatotroph pituitary tumor signal intensity in T-2 weighted pituitary MR images- quantitative assessment of the parameter and its clinical implications in consecutive newly-diagnosed patients with acromegaly.

Patients with atopy exhibit attenuated neuroendocrine response during psychosocial stress  

Treatment of Cushing’s disease (CD) after primary failure of transsphenoidal surgery or recurrence: evaluation of long-term control by drug treatment

Epicardial and pericardial adiposity without myocardial steatosis in Cushing’s syndrome

Impact of a specific rehabilitation program on the quality of life of patients with a Cushing's syndrome

Circadian clock and muscle wasting associated with impaired insulin signalling: in vitro effect of hydrocortisone circadian administrations.

Functional characterization of beta-arrestin 1 in neuroendocrine tumor cell lines

CLINICAL AND LABORATORY CHARACTERISTICS OF HYPERANDROGENISM IN WOMEN WITH HYPERPROLACTINEMIA

Gonadotroph Pituitary Adenoma or Andropause

Gonadotropic function of patients with inactive pituitary adenoma (IPA)  

Clinical characterization of insulin resistance in patients with different pituitary adenomas

Features of cognitive dysfunction in patients with hyperprolactinemia of various  etiology

Androgen-secreting tumors in adrenals in gender and age aspects

GDF15 value in predicting cardio-vascular outcomes  in patients with ACTH depended Cushing syndrome in the Republic of Uzbekistan

Challenging case of perioperative management of paraganglioma  

Clinical manifestations of musculoskeletal complications of acromegaly.