Testing the recovery of the axis in tertiary adrenal insufficiency

Hypopituitarism and pregnancy

Hormone receptor targets in neuroendocrine tumours

Chairs : Maria TICHOMIROWA (LUXEMBOURG), Marek BOLANOWSKI (POLAND)

The year in neuroendocrinology - basic

The year in neuroendocrinology - clinical

Chairs : Marily THEODOROPOULOU (GERMANY)

A time to fast, a time to feast: interaction between chronobiological and neuroendocrine systems

Chairs : Raul LUQUE (SPAIN), Gérald RAVEROT (FRANCE)

Synaptic communication & reproductive circuits

Stem cell-derived paracrine signals in pituitary homeostasis

Clinical Imaging of the pituitary stalk

New biochemical tools in the diagnosis and follow up of Cushing's disease

Clinical management of MEN 1

Probing genome’s architecture in cell plasticity and disease

Chairs : Pedro MARQUES (PORTUGAL), Juan Manuel JIMÉNEZ VACAS (UNITED KINGDOM)

Molecular mechanisms of cavernous sinus invasion by pituitary adenomas: in vitro studies and in vivo investigations in a rat model of invasive pituitary tumorigenesis obtained by stereotactic pituitary GC cells injection

Circulating microRNAs as predictors for dopamine agonists in hyperprolactinemic patients with pituitary adenoma

Effect of a novel somatostatin receptor 5/3 agonist, HTL0030310, on human GH- and ACTH-secreting pituitary adenomas in vitro  

Xq26.3 duplications in X-linked acrogigantism (X-LAG) disrupt a topologically associating domain (TAD) and rewire GPR101-enhancer interactions

Morphological and molecular evidence of macroautophagy in pituitary tumors

New provocation test using MDMA (‘Ecstasy’) demonstrates Oxytocin deficiency in patients with central diabetes insipidus

Association between use of systemic and inhaled glucocorticoids and changes in brain volume and white matter microstructure: a cross-sectional UK Biobank study

CRN04894: an oral, nonpeptide ACTH (MC2) receptor antagonist decreaseds basal and stimulated cortisol secretion in healthy volunteers 

Chairs : Juan Pedro MARTINEZ-BARBERA (UNITED KINGDOM)

The molecular design of hypothalamus development

Pull your SOXs up! - From stem cells to pituitary tumors

Chairs : Giampaolo TRIVELLIN (ITALY), Luis G. PÉREZ-RIVAS (GERMANY)

The Molecular Basis of Congenital Hypopituitarism

Dysregulated peptide amidation as a new cause of hypopituitarism

Human iPS cells as model for congenital hypopituitarism

Efficacy and predictive factors of response to immunotherapy in pituitary carcinomas and aggressive pituitary tumors: a French cohort study

High prevalence of genetic predisposition in young men and women with lactotrop macroadenomas

Prolactinomas: resistance assessment via metabolomic characteristics

Impact of the diagnostic delay of acromegaly on bone health: data from a real life and long term follow-up experience

Clinical and translational evidence of metformin and simvastatin additive antitumor effects in glioblastoma via senescence-state

Somatic hotspot variants rarely coexist with germline drivers of Cushing’s disease

Clinicopathological characteristics, clinical outcome, and prognostic factors for pituitary carcinomas: lessons from a systematic review of 207 cases

Dissecting the in vitro efficacy of octreotide and cabergoline in GH- and GH/PRL-secreting pituitary tumors

Somatostatin and ghrelin systems characterization and therapeutic potential in liver diseases

Neoadjuvant B-RAF and MEK inhibitor targeted therapy for Adult Papillary Craniopharyngiomas: A new treatment paradigm

Volumetric BMD and bone strength estimates on QCT-based finite element analysis are impaired in patients with Cushing’s syndrome in long-term remission

Prevalence of somatic SF3B1 mutations in lactotroph tumours

Lysine demethylase KDM1A and ectopic expression of GIP-receptor in somatotroph adenomas

Discrimination of pituitary neuroendocrine tumours by Raman spectroscopy

Central diabetes insipidus from a patients’ perspective: management, psychological co-morbidities and re-naming of the condition

Circulating miR-28-5p is a potential biomarker of sarcopenia in patients with Cushing’s syndrome in remission

The effect of glucose dynamics on plasma copeptin levels upon glucagon, arginine, and macimorelin stimulation in healthy adults

Resistance to cabergoline treatment in human primary non-functioning pituitary tumour cells

Cabergoline add-on therapy in patients with uncontrolled acromegaly under somatostatin analogues – a multicenter, retrospective, cohort study of non-irradiated patients applying current criteria for disease control  

Chairs : Maria Chiara ZATELLI (ITALY), Andrea ISIDORI (ITALY)

From the Patient to cell culture and back : personalized drug testing NETs

Kisspeptin: puberty and beyond

How to manage recurrent nonfunctioning pituitary tumours

Chairs : Antoine TABARIN (FRANCE)

POMC neurons and energy balance: a tale with many twists and surprises

Chairs : Monica MARAZUELA (SPAIN), Marija PFEIFER (SLOVENIA)

Oxytocin and social behavior

New diagnostic tests in diabetes insipidus

Management of hyponatermia in different clinical scenarios

Intraoperative discrimination of tumour and healthy tissue using spectroscopy

Cushing's syndrome due to ectopic ACTH secretion

Pituitary tumours in pregnancy

Long-term treatment with oral paltusotine for acromegaly: Results from the ACROBAT Advance study 

Debio 4126, a new 3-month octreotide formulation, provides sustained release of octreotide, as well as enhanced bioavailability and similar suppression of insulin-like growth factor 1 (IGF-1), compared to monthly Sandostatin LAR in healthy volunteers - interim results

Genetic aspects of adrenal incidentalomas

Outcomes in patients receiving oral octreotide capsules related to time from last somatostatin receptor ligand injection: analysis from the MPOWERED Phase 3 study

Clinical-imagine asessment of agressive pituitary adenomas

Patterns of somatostatin receptor ligand dosage and titration in patients with acromegaly: a real-world evidence study

First-generation somatostatin receptor ligands in the treatment of acromegaly: real-world patient journey

Treatment of hypothalamic obesity with GLP-1 agonists and extreme diet in a patient with hypothalamic inflammatory infiltration

Clinical case of syndrome of inappropriate secretion of antidiuretic hormone (SIADH) with uncertain localization

Vanishing pituitary lesion with intermittent central adrenal insufficiency

ACROMEGALY DUE TO  A GH-SECRETING PITUITARY ADENOMA IN THE SPHENOID SINUS

Morning and evening concentrations of salivary aldosterone and cortisol throughout the menstrual cycle in healthy women

Observation of bone mineral density in Cushing syndrome

The various clinical outcomes of giant prolactinomas in men

The endoscopic endonasal resection of giant pituitary neuroendocrine tumors - case series from the referral pituitary center.

Results of surgical treatment of the Rathke cleft cysts with endoscopic endonasal cyts evacualtion – clinical series from pituitary referral center.

Impact of the micro nutriments’ deficit on the functional disorders for diabetic menopause women.

Health-Related Quality of Life Burden in Endogenous Cushing’s Syndrome: A Retrospective Medical Chart Audit Study

Gonadotroph Adenomas. A Single-Center Study of 112 cases.

Chairs : Leo HOFLAND (NETHERLANDS), Hervé LEFEBVRE (FRANCE)

Cell- and tissue specificity of gluocorticoids actions.

Long-term consequences of hypercortisolism

Epigenetic modulation by glucocorticoids

Short presentation: Bone consequences of chronic hypercortisolism

Chairs : Yona GREENMAN (ISRAEL), Anne BARLIER (FRANCE)

Transcriptomic Signature of Pituitary NeuroEndocrine Tumors (PitNETs) aggressiveness

Single nucleus multiomics identifies inter- and intra-donor heterogeneity in pituitary neuroendocrine tumors/pituitary adenomas

High-risk pituitary adenomas: lessons learned and summary on the eve of the new classification - a clinicopathologic case series from the referral pituitary center.

Neoadjuvant or Adjuvant treatment of mutant BRAF-V600E papillary Craniopharyngioma (Swecranio1-21)

Serum soluble alpha klotho in patients with growth hormone deficiency

Immunoglobulin G is an oxytocin-binding protein in plasma – role in oxytocin receptor activation and relevance to aggressive behavior  

Chairs : Atanaska ELENKOVA (BULGARIA)

Increased cancer risk in acromegaly patients – the never ending controversy

Real-time detection of acromegaly from facial images with artificial intelligence

The MPOWERED Phase 3 Trial : Oral Octreotide Outcomes based on IGF-I Response Criteria

Improvements in hypertension and diabetes mellitus with osilodrostat in Cushing’s disease patients: Exploratory analyses from the Phase III LINC 3 study

Molecular dissection of the GIP/GIPR axis in a stable cell model of GH-secreting pituitary adenomas

Implementation of functional imaging using 11C-methionine PET-CT co-registered with MRI for advanced surgical planning and decision making in prolactinoma surgery

Chairs : Alexandre VASILJEVIC (FRANCE)

Imprinting in hypothalamus-pituitary pathology

Non-coding RNAs: mere messengers or causative factors?

Pituitary tumor microenvironment

Chairs : Jérôme BERTHERAT (FRANCE), Patrick PETROSSIANS (BELGIUM)

Nelson's syndrome

Recent Consensus in Cushing's syndrome: the clinical agenda

Chairs : Emmanuel JOUANNEAU (FRANCE), Krystallenia ALEXANDRAKI (GREECE)

Emerging pharmacological therapies for craniopharyngiomas

Craniopharyngioma: relapse

Surgical indications and limitations for recurrent pituitary tumors & craniopharyngiomas

Questions

Update on temozolomide: results of a European Society of Endocrinology (ESE) survey

What is the role of pathology?

Immunotherapy for aggressive pituitary tumours & carcinomas